Table 1.

Correlation coefficients between signal evolutions during the multipulse acquisition. The correlation coefficients were calculated between signal evolutions from three different compartments in the phantom (0%, 4%, and 8% agar) and in brain (CSF, IC, and EC), as measured in ROIs in the phantom compartments (first column), as well as from signal simulations in both phantom and brain, before and after $B_1^{+}$ and frequency offset correction (second and third column, respectively). Correlation coefficients between 4% and 8% agar compartments signal developments are around 0.7. Simulated signal developments from IC and EC compartments in human brain tissue for the present 15-pulse sequence show correlations of around 0.1. Abbreviations: CSF, EC, and IC stand for cerebrospinal fluid, extracellular, and intracellular compartments in the brain.

	Measured	Correlation Simulated Before Correction	Simulated After Correction
Phantom
0% and 4% Agar	0.55	0.41	0.57
0% and 8% Agar	0.05	0.01	0.04
4% and 8% Agar	0.67	0.77	0.70
Brain
CSF and EC		0.23	0.32
CSF and IC		−0.52	−0.41
EC and IC		0.02	0.12