Table 1.
Patient characteristics in PLC compared to IDC.a
| Variables | IDC, n = 460,109 (%) | PLC, n = 131 (%) | Total, n = 460,240 (%) | P b | |
|---|---|---|---|---|---|
| Median survival months | 105.2 ± 64.39 | 84 ± 51.03 | 105.01 ± 64.39 | <0.01 | |
| Year of diagnosis | 1990–1999 | 153,948 (33.5) | 13 (9.9) | 153,961 (33.5) | <0.01 |
| 2000–2009 | 306,161 (66.5) | 118 (90.1) | 306,279 (66.5) | ||
| Age at diagnosis | 15–49 | 112,714 (24.5) | 28 (21.4) | 112,742 (24.5) | 0.466 |
| 50–85+ | 347,395 (75.5) | 103 (78.6) | 347,498 (75.5) | ||
| Race | Black | 41,804 (9.1) | 21 (16.0) | 41,825 (9.1) | 0.018 |
| White | 379,964 (82.6) | 98 (74.8) | 380,062 (82.6) | ||
| Othersc | 38,341 (8.3) | 12 (9.2) | 38,353 (8.3) | ||
| Marital status | Married | 387,230 (84.2) | 102 (77.9) | 387,332 (84.2) | 0.023 |
| Unmarriedd | 56,805 (12.3) | 19 (14.5) | 56,824 (12.3) | ||
| Unknown | 16,074 (3.5) | 10 (7.6) | 16,084 (3.5) | ||
| Laterality | Left | 233,561 (50.8) | 62 (47.3) | 233,623 (50.8) | 0.485 |
| Right | 226,548 (49.2) | 69 (52.7) | 226,617 (49.2) | ||
| Grade | I | 75,619 (16.4) | 1 (0.8) | 75,620 (16.4) | <0.01 |
| II | 176,421 (38.3) | 41 (31.3) | 176,462 (38.3) | ||
| III | 166,700 (37.3) | 57 (43.6) | 166,757 (37.3) | ||
| Unknown | 36,369 (7.9) | 32 (24.4) | 36,401 (7.9) | ||
| AJCC stage | 0 | 21 (0.0) | 0 (0.0) | 21 (0.0) | <0.01 |
| I | 213,644 (46.4) | 34 (26) | 213,678 (46.4) | ||
| II | 145,408 (31.6) | 59 (45.0) | 145,467 (31.6) | ||
| III | 54,398 (11.8) | 25 (19.1) | 54,423 (11.8) | ||
| IV | 15,827 (3.4) | 5 (3.8) | 15,832 (3.4) | ||
| Unknown | 30,811 (6.7) | 8 (6.1) | 30,819 (6.7) | ||
| LN status | Negative | 257,886 (56.0) | 59 (45) | 257,945 (56) | <0.01 |
| Positive | 137,444 (29.9) | 56 (42.7) | 137,500 (29.9) | ||
| Unknown | 64,779 (14.1) | 16 (12.2) | 64,795 (14.1) | ||
| ER status | Negative | 97,679 (21.2) | 34 (26) | 97,713 (21.2) | 0.351 |
| Positive | 303,405 (65.9) | 79 (60.3) | 303,484 (65.9) | ||
| Unknown | 59,025 (12.8) | 18 (13.7) | 59,043 (12.8) | ||
| PR status | Negative | 137,281 (29.8) | 43 (32.8) | 137,324 (29.8) | 0.748 |
| Positive | 255,245 (55.5) | 69 (52.7) | 255,314 (55.5) | ||
| Unknown | 67,583 (14.7) | 19 (14.5) | 67,602 (14.7) | ||
| Surgery type | Mastectomy | 139,769 (30.4) | 71 (54.2) | 139,840 (30.4) | <0.01 |
| Lumpectomy | 185,118 (40.2) | 46 (35.1) | 185,164 (40.2) | ||
| No surgery | 16,730 (3.6) | 5 (3.8) | 16,735 (3.6) | ||
| Unknown | 118,492 (25.8) | 9 (6.9) | 118,510 (25.8) | ||
| Radiation | Yes | 212,702 (46.2) | 49 (37.4) | 212,751 (46.2) | 0.048 |
| No | 234,239 (50.9) | 75 (57.3) | 234,314 (50.9) | ||
| Unknown | 13,168 (2.9) | 7 (5.3) | 13,175 (2.9) | ||
AJCC, American Joint Committee on Cancer; ER, estrogen receptor; PLC, Pleomorphic lobular breast carcinoma; IDC, infiltrating ductal carcinoma; LN, lymph node; PR, progesterone receptor.
a
The data are presented as the No. (percentage) of patients unless otherwise indicated.
b
P‐value of the Chi‐square test to compare the PLC and IDC groups. The value of bold is statistically significant.
c
Including American Indian/Alaskan native, Asian/Pacific Islander, and others‐unspecified.
d
Including divorced, separated, single (never married), and widowed.