Table 5.
ER‐positive patient characteristics in PLC compared to IDCa
| Variables | IDC n = 303,405(%) | PLC n = 79(%) | Total n = 303,484(%) | P‐valueb | |
|---|---|---|---|---|---|
| Median survival months | 105.7 ± 61.154 | 86.71 ± 44.525 | <0.01 | ||
| Year of diagnosis | 1990–1999 | 93,315 (30.8) | 4 (5.1) | 93,319 (30.7) | <0.01 |
| 2000–2009 | 210,090 (69.2) | 75 (94.9) | 210,165 (69.3) | ||
| Age at diagnosis | 15–49 | 67,108 (22.1) | 14 (17.7) | 67,122 (22.1) | 0.420 |
| 50–85+ | 236,297 (77.9) | 65 (82.3) | 236,362 (77.9) | ||
| Race | Black | 21,190 (7.0) | 9 (11.4) | 21,199 (7.0) | 0.254 |
| White | 256,106 (84.4) | 62 (78.5) | 256,188 (84.4) | ||
| Otherc | 26,109 (8.6) | 8 (10.1) | 26,117 (8.6) | ||
| Marital status | Married | 257,816 (85.0) | 66 (83.5) | 257,882 (85.0) | 0.055 |
| Unmarriedd | 36,195 (11.9) | 7 (8.9) | 36,202 (11.9) | ||
| Laterality | Left | 153,103 (50.5) | 38 (48.1) | 153,141 (50.5) | 0.759 |
| Right | 150,302 (49.5) | 41 (51.9) | 150,343 (49.5) | ||
| Grade | I | 64,652 (21.3) | 1 (1.3) | 64,653 (21.3) | <0.01 |
| II | 138,298 (45.6) | 35 (44.3) | 138,333 (45.6) | ||
| III | 82,044 (27) | 24 (30.3) | 78,280 (27) | ||
| Unknown | 18,411 (6.1) | 19 (24.1) | 18,430 (6.1) | ||
| AJCC stage | I | 153,897 (50.7) | 26 (32.9) | 153,923 (50.7) | <0.01 |
| II | 93,087 (30.7) | 28 (35.4) | 93,115 (30.7) | ||
| III | 31,848 (10.5) | 18 (22.8) | 31,866 (10.5) | ||
| IV | 9028 (3.0) | 3 (3.8) | 9031 (3.0) | ||
| Unknown | 15,531 (5.1) | 4 (5.1) | 15,535 (5.1) | ||
| LN status | Negative | 175,444 (57.8) | 37 (46.8) | 175,481 (57.8) | 0.059 |
| Positive | 89,877 (29.6) | 33 (41.8) | 89,910 (29.6) | ||
| Unknown | 38,084 (12.6) | 9 (11.4) | 38,093 (12.6) | ||
| PR status | Negative | 48,553 (16.0) | 12 (15.2) | 48,565 (16.0) | 0.996 |
| Positive | 246,280 (81.2) | 65 (82.3) | 246,345 (81.2) | ||
| Unknown | 8572 (2.8) | 2 (2.5) | 8574 (2.8) | ||
| Surgery type | Mastectomy | 89,954 (29.6) | 44 (55.7) | 89,998 (29.7) | <0.01 |
| Lumpectomy | 134,125 (44.2) | 29 (36.7) | 134,154 (44.2) | ||
| No surgery | 8916 (2.9) | 4 (5.1) | 8920 (2.9) | ||
| Unknown | 278 (0.1) | 0 (0) | 278 (0.1) | ||
| Radiation | No | 145,644 (48.0) | 40 (50.6) | 145,684 (48.0) | <0.01 |
| Yes | 149,760 (49.4) | 32 (40.5) | 149,778 (49.4) | ||
| Unknown | 8015 (2.6) | 7 (8.9) | 8022 (2.6) | ||
AJCC, American Joint Committee on Cancer; ER, estrogen receptor; PLC, Pleomorphic lobular breast carcinoma; IDC, infiltrating ductal carcinoma; LN, lymph node; PR, progesterone receptor.
a
The data are presented as the No. (percentage) of patients unless otherwise indicated.
b
P‐value of the Chi‐square test to compare the PLC and IDC groups. The value of bold is statistically significant.
c
Including American Indian/Alaskan native, Asian/Pacific Islander and others‐unspecified.
d
Including divorced, separated, single (never married), and widowed.