Table 2.
Relationship between clinicopathological characteristics and tumor necrosis
| No tumor necrosis | Tumor necrosis | P‐value | |
|---|---|---|---|
| (n = 618) | (n = 122) | ||
| Sex | 0.210 | ||
| Male | 301 | 67 | |
| Female | 317 | 55 | |
| Age (years) | 0.276 | ||
| <60 | 317 | 56 | |
| ≥60 | 301 | 66 | |
| Tumor size (cm) | <0.001 | ||
| ≤5 | 443 | 32 | |
| >5 | 175 | 90 | |
| Mitotic index (/50 HPF) | <0.001 | ||
| <5 | 480 | 58 | |
| ≥5 | 138 | 64 | |
| Tumor location | 0.058 | ||
| Upper third | 301 | 48 | |
| Middle/lower third | 317 | 74 | |
| Histological subtype | 0.295 | ||
| Spindle type | 561 | 107 | |
| Epithelioid/mixed type | 57 | 15 | |
| Tumor rupture | 0.009 | ||
| No | 616 | 119 | |
| Yes | 2 | 3 | |
| Nuclear atypia | <0.001 | ||
| No | 519 | 75 | |
| Yes | 37 | 26 |