Table 1.

Fraction of each seed mutation in each of six replicate populations after 55 generations of selection

Replicate	Mutation fraction in population
	1	2	3	4	5	6
rpoC1022	0.911 ± 0.039	0.839 ± 0.055	0.868 ± 0.025	0.936 ± 0.019	0.821 ± 0.011	0.805 ± 0.019
cyaA797	0.003 ± 0.001	0.002 ± 0.001	0.001 ± 0.001	0.001 ± 0.001	0.007 ± 0.002	0.003 ± 0.001
cyaA2227	0.498 ± 0.056	0.181 ± 0.018	0.252 ± 0.028	0.326 ± 0.056	0.455 ± 0.031	0.088 ± 0.008
glpK695	0.007 ± 0.001	0.019 ± 0.006	0.015 ± 0.004	0.010 ± 0.005	0.155 ± 0.056	0.018 ± 0.006
glpK288	0.399 ± 0.106	0.672 ± 0.022	0.832 ± 0.012	0.592 ± 0.063	0.367 ± 0.019	0.840 ± 0.008
glpK694	0.426 ± 0.055	0.260 ± 0.073	0.109 ± 0.034	0.495 ± 0.097	0.504 ± 0.060	0.151 ± 0.025
Total	2.244 ± 0.137	1.978 ± 0.096	2.077 ± 0.052	2.360 ± 0.130	2.309 ± 0.090	1.905 ± 0.034

Errors in s.d. (n = 3 technical replicates)