Table 2.
Potential determinants of the rapid S100A8/A9 response induced by acute psychological stress in CAD patients (Study I).
| Spearman correlation | Multivariable linear regression* | |||
|---|---|---|---|---|
| r | P | Beta coefficient | P | |
| Age | 0.029 | n.s. | −0.100 | n.s. |
| Sex | — | — | 0.098 | n.s. |
| BMI | −0.148 | n.s. | −0.274 | n.s. |
| Diabetes | — | — | 0.068 | n.s. |
| Hypertension | — | — | −0.138 | n.s. |
| Smoking | — | — | −0.029 | n.s. |
| Plasma lipids | ||||
| Total cholesterol | −0.033 | n.s. | — | — |
| LDL | −0.087 | n.s. | −0.211 | n.s. |
| HDL | −0.061 | n.s. | −0.124 | n.s. |
| TG | −0.100 | n.s. | −0.050 | n.s. |
| Circulating cell populations | ||||
| Leukocytes | 0.113 | n.s. | — | — |
| Neutrophils | 0.154 | n.s. | −0.106 | n.s. |
| Monocytes | 0.048 | n.s. | 0.041 | n.s. |
| Lymphocytes | 0.011 | n.s. | −0.101 | n.s. |
| Saliva cortisol | ||||
| Morning | −0.006 | n.s. | 0.165 | n.s. |
| Evening | 0.315 | 0.016 | 0.635 | 0.004 |
| Cortisol response to stress# | 0.032 | n.s. | 0.218 | n.s. |
| Medication | ||||
| Statin | — | — | −0.049 | n.s. |
| Betablocker | — | — | 0.082 | n.s. |
| ACE/ARB | — | — | 0.205 | n.s. |
| Calcium-channel blockers | — | — | 0.038 | n.s. |
*Multivariable linear regression with stress-induced S100A8/A9 increase, expressed as percentage of baseline, as dependent variable.
#Percent cortisol increase at 20 minutes after the stress test compared to baseline.