Table 5.
Baseline characteristics in patient groups with high and low APN value.
| Parameters | APN < 14,2 μg/ml | APN ≥ 14.2 μg/ml | p value |
|---|---|---|---|
| Sex | M: 23 (85.2%) F: 4 (14.8%) |
M: 21 (75%) F: 7 (25%) |
0.345 |
| NYHA class | I + II: 4 (15.4%) III: 20 (76.9%) IV: 2 (7.7%) |
I + II: 2 (7.4%) III: 16 (59.3%) IV: 9 (33.3%) |
0.061 |
| Age (years) | 48.19 ± 8.29 | 46.96 ± 12.89 | 0.679 |
| BMI∗ (kg/m2) | 27.92 ± 5.70 | 24.41 ± 9.00 | 0.168 |
| GFR (ml/min) | 111.78 ± 27.66 | 110.70 ± 36.64 | 0.907 |
| Systolic BP (mmHg) | 121 ± 21 | 112 ± 20 | <0.0002 |
| Diastolic BP (mmHg) | 75 ± 10 | 80 ± 10 | 0.647 |
| Serum glucose (mmol/l) | 5.38 ± 1.07 | 5.38 ± 2.39 | 0.913 |
| BNP∗ (pg/ml) | 113.8 ± 694.35 | 1397 ± 2338.5 | <0,001 |
| IL-6∗ (pg/ml) | 2,01 ± 4.27 | 3,18 ± 6.08 | 0.245 |
| TNF-α∗ (pg/ml) | 7.54 ± 3.18 | 9.09 ± 2.54 | 0.029 |
| CRP∗ (ug/ml) | 3.05 ± 6.53 | 6.15 ± 13.23 | 0.252 |
| TnT∗ (pg/ml) | 23.55 ± 28.28 | 31,00 ± 31.76 | 0.368 |
| LV DD (cm) | 6.80 ± 0,80 | 6.95 ± 0.94 | 0.548 |
| EF (%) | 27.15 ± 9.60 | 26.22 ± 9.50 | 0.493 |
| Average global strain (%) | −9.26 ± 3.42 | −7.09 ± 3.38 | 0.051 |
| CD3+∗ (cells/mm2) | 10 ± 5 | 11 ± 10 | 0.364 |
| CD45ro+∗ (cells/mm2) | 6 ± 3 | 7 ± 5 | 0.493 |
| CD68+∗ (cells/mm2) | 5 ± 2 | 5 ± 2 | 0.769 |
| Mean RAP∗ (mmHg) | 11.00 ± 8.00 | 11.50 ± 11.50 | 0.099 |
| Mean PAP∗ (mmHg) | 25.5 ± 13.00 | 37.0 ± 19.00 | 0.036 |
| Mean PCWP (mmHg) | 19.50 ± 8.26 | 24.12 ± 8.73 | 0.083 |
| CO (l/min)∗ | 4.9 ± 2.77 | 3.9 ± 1.32 | 0.035 |
| CI (l/min/m2)∗ | 2.29 ± 1.12 | 2.05 ± 0.89 | 0.131 |
BMI: body mass index, GFR: glomerular filtration rate, APN: adiponectin, BNP: brain natriuretic peptide, IL-6: interleukin-6, TNF-α: tumor necrosis factor α, CRP: C reactive protein, hsTnT: high sensitivity troponin T, LVEDD: left ventricle diastolic diameter, LVEF: left ventricle ejection fraction, CD3+: T cell receptor, CD45ro+: memory T cell receptor, CD68+: monocyte/macrophage receptor, RAP: right atrial pressure, PAP: pulmonary artery pressure, PCWP: pulmonary capillary wedge pressure, CO: cardiac output, and CI: cardiac index. ∗Data presented as median ± interquartile range. Significant at the p level 0.05 (2-tailed).