Fig. 5.

Quantification of mitochondrial number and neuronal cytoplasmic density in control (Cont) and CM-treated (CM) rats. Number of mitochondria in cortical neuronal (A), pyramidal (B), Purkinje (C) and anterior horn (D) cell bodies per 50 μm² and in cardiomyocytes (E) per 20 μm in length between myofibrils. Cytoplasmic density, shown by electron micrographs, in cortical neuronal cell bodies (F), pyramidal cell bodies (G) and dendrites (H), Purkinje cell bodies (I) and dendrites (J), anterior horn cell bodies (K) and myelinated axons (L). The number of mitochondria was significantly (* P < 0.05) less in cortical neurons and pyramidal cells but greater (** P < 0.01) in cardiomyocytes in CM-treated rats. The cytoplasmic density values from the control rats were normalized using 100 as a mean value for arbitrary units (AU), and all images showed significantly (* P < 0.05, ** P <0.01) lower levels in CM-treated rats.