Table 2. Phenotypic and genetic features associated with OXA-204-beta-lactamase producing Enterobacteriaceae, France, 2012–14 (n = 29).

Species /clone	Number of isolates	Sequence type	Beta-lactams MIC range (µg/mL)			Genetic location of blaOXA-204	Incompatibility group of blaOXA-204-carrying plasmid	Non-beta-lactam-associated resistance (number of strains)	Associated broad-spectrum beta-lactamasesa (number of strains)	Close genetic environment of the blaOXA-204 gene
			ERT	IMP	MER
Escherichia coli
A	12	ST90	0.38–32	0.19–12	0.094–6	Plasmid	IncA/C	Gm (12), Tm (12), Q (12), Tet(12), Sxt (10)	CMY-4 (12), CTX-M-15 (9)	Tn2016
B	1	ST104	0.5	0.38	0.25	Plasmid	IncA/C	Tet	CMY-4	ISEcp1
C	1	ST617	1	0.25	0.25	Plasmid	IncA/C	Gm, Tm, Q, Tet, Sxt	CMY-4	Tn2016
D	1	ST949	0.75	0.5	0.19	Plasmid	IncA/C	Q, Tet, Sxt	CMY-4	ISEcp1
Klebsiella pneumoniae
A	9	ST147	3– >32	1–12	1– >32	Plasmid	IncA/C	Ak (1), Tm (8), Gm (6), Q (9), Tet (9), Sxt (8), Fos (7)	CMY-4 (9), CTX-M-15 (9)	ISEcp1
B	1	ST1683b	3	0.25	0.19	Plasmid	IncA/C	Gm, Tm, Tet	CMY-4	Tn2016
C	1	ST1709b	1	0.25	0.12	Plasmid	IncA/C	Gm, Tm, Tet, Tig	CMY-4	Tn2016
Proteus mirabilis	1	ND	1.5	0.38	0.094	Plasmid	IncA/C	Gm, Tm, Sxt	CMY-4	ISEcp1
Citrobacter freundii	1	ND	3	1	0.5	Plasmid	IncA/C	Gm, Tm, Q, Tet, Tig	CMY-4	Tn2016
Serratia marcescens	1	ND	0.75	0.75	0.5	Plasmid	IncA/C	Gm, Tm, Tet, Tig	CMY-4	Tn2016

Ak: amikacin; ERT: ertapenem; Fos: fosfomycin; Gm: gentamicin; IMP: imipenem; MER: meropenem; MIC: minimum inhibitory concentration; ND: not determinable; Q: quinolones; Sxt: sulfamethoxazole-trimethoprim; Tet: tetracycline; Tig: tigecycline; Tm: tobramycin.

^a Resistance markers co-harboured on the bla _OXA-204-carrying plasmid are underlined.

^b ST1683 ad ST1709 are new sequence types.