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. 2017 Oct 23;14(6):7653–7668. doi: 10.3892/ol.2017.7261

Table II.

Markers of colorectal cancer stem cells.

Author, year Marker Function (Refs.)
Ricci-Vitiani et al, 2007; CD133 Prominin-1; membrane glycoprotein, present on (13,177179)
Botchkina, 2013; the surface of actively proliferating stem cells;
Haraguchi et al, 2008; function unknown
Zhu et al, 2009
Manhas et al, 2016; CD44 P Glycoprotein 1; membrane hyaluronic acid receptor (2,23,26,178,180)
Vermeulen et al, 2008;
Du et al, 2008;
Haraguchi et al, 2008;
Botchkina et al, 2009
Manhas et al, 2016; CD166 ALCAM; membrane glycoprotein, adhesion molecule (2,23,180)
Vermeulen et al, 2008;
Botchkina et al, 2009
Huang et al, 2009; ALDH1 Aldehyde dehydrogenase, detoxification enzyme, transforms (16,181)
Zhou et al, 2015 retinol to retinoic acid, which regulates proliferation of cells
Vermeulen et al, 2008 CD29 β1 integrin, adhesion molecule (23)
Manhas et al, 2016; CD24 Heat-stable antigen; membrane glycoprotein, (2,23)
Vermeulen et al, 2008 adhesion molecule
Manhas et al, 2016 ESA Epithelial specific antigen, EpCAM, CD326; membrane (2)
glycoprotein, adhesion and signaling molecule;

ALDH1, aldehyde dehydrogenase 1; ESA, epithelial-specific antigen; ALCAM, activated leukocyte cell adhesion molecule; EpCAM, epithelial cell adhesion molecule.