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Association between (A) the circadian sub-network and (B) HepG2 HUB-sub-network. Yellow represents CKAP5, the HepG2 HUB-genes and four circadian seed genes (CLOCK, CSNK1E, CSNK1D and HDAC4), which are directly connected via CKAP5. The other genes present in circadian and HepG2 HUB sub-networks are indicated in green and blue, respectively. CKAP5, cytoskeleton associated protein 5; CLOCK, clock circadian regulator; CSNK, casein kinase; HDAC4, histone deacetylase 4.
