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. 2017 Nov 28;2017:3824276. doi: 10.1155/2017/3824276

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Copyright © 2017 Shoucui Gao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Generation and identification of human CETP Tg rabbits. (a) Tg construct for the microinjection. (b) Identification of the integration of the human CETP transgene in the rabbit genome by PCR (M: DNA marker; +: positive control plasmid; −: negative control; lanes 1–13: rabbit DNA sample). (c) Tissue distribution of human CETP mRNA in Tg and non-Tg rabbits (n = 3 for each group). (d) Western blotting analysis of CETP from liver and plasma (n = 3 for each group). (e) Plasma CETP activity (n = 4 for each group). (f) Plasma human CETP concentrations (n = 7 for each group). Data are expressed as the mean ± SEM. ^∗∗∗P < 0.001 versus non-Tg littermates.