Table 2.
Genotype and allele distributions for the TNFR1 (rs4149576, rs4149577, and rs1860545) SNPs in patients with and without family history of schizophrenia and suicide attempts.
| Polymorphisms | N (%) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Genotype | Allele | ||||||||
| rs4149576 | T/T | C/T | C/C | χ 2 | p | T | C | χ 2 | p |
| With family history | 24 (25) | 48 (51) | 23 (24) | 0.41 | 0.81 | 96 (49) | 94 (51) | 0.23 | 0.67 |
| Without family history | 84 (29) | 142 (48) | 67 (23) | 276 (47) | 310 (53) | ||||
| With suicide attempts | 17 (23) | 41 (55) | 16 (22) | 1.64 | 0.43 | 75 (51) | 73 (49) | 0.12 | 0.72 |
| Without suicide attempts | 91 (29) | 149 (47) | 74 (24) | 331 (53) | 297 (47) | ||||
| rs4149577 | A/A | A/G | G/G | χ 2 | p | A | G | χ 2 | p |
| With family history | 31 (33) | 48 (50) | 16 (17) | 0.09 | 0.95 | 110 (58) | 80 (42) | 0.01 | 0.92 |
| Without family history | 91 (31) | 153 (52) | 49 (17) | 335 (57) | 251 (43) | ||||
| With suicide attempts | 23 (31) | 40 (54) | 11 (15) | 0.28 | 0.86 | 86 (58) | 62 (42) | 0.01 | 0.90 |
| Without suicide attempts | 99 (32) | 161 (51) | 54 (17) | 359 (57) | 269 (43) | ||||
| rs1860545 | G/G | G/A | A/A | χ 2 | p | A | G | χ 2 | p |
| With family history | 26 (27) | 46 (49) | 23 (24) | 0.47 | 0.78 | 92 (48) | 98 (52) | 0.29 | 0.58 |
| Without family history | 70 (24) | 147 (50) | 76 (26) | 299 (51) | 287 (49) | ||||
| With suicide attempts | 17 (23) | 41 (55) | 16 (22) | 1.24 | 0.53 | 73 (49) | 75 (51) | 0.03 | 0.84 |
| Without suicide attempts | 79 (25) | 152 (48) | 83 (27) | 318 (51) | 310 (49) | ||||