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. 2017 Nov 28;2017:4139439. doi: 10.1155/2017/4139439

Figure 5.

Figure 5

Effects of gemigliptin pretreatment on cisplatin-induced inflammatory responses. Plasma levels of TNF-α (a) and MCP-1 (b). (c) Immunohistochemical staining of nuclear NF-κB p65 in the kidneys (×200). Red arrows indicate cells showing nuclear p65-positive staining. (d) The number of NF-κB-activated cells in 10 fields (×200). Con: control, n = 6; CP: cisplatin, n = 6; and CP + G: cisplatin + gemigliptin, n = 6. All data are expressed as the mean ± SEM. #P < 0.01 versus Con, ∗P < 0.05 versus CP, and ∗∗P < 0.01 versus CP.