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. 2017 Nov 26;2017:3619879. doi: 10.1155/2017/3619879

Figure 2.

Figure 2

Ta-EE reduced the serum levels of inflammatory mediators and proinflammatory cytokines in MIA-induced OA rats. MIA-induced OA rats were orally administered with either Ta-EE (30–120 mg/kg), MSM (155 mg/kg), or Pc-LE (20 mg/kg) once a day, and the levels of (a) PGE2, (b) LTB4, (c) IL-1β, and (d) IL-6 in the sera of the rats in each group were measured at weeks zero, two, and four. ∗P < 0.05, ∗∗P < 0.005 versus a control group; #P < 0.05 and ##P < 0.005 versus a normal group; +P < 0.05 and ++P < 0.005 week 0 versus week 2 or 4; &P < 0.05 and &&P < 0.005 week 2 versus week 4.