Table 1.

Potential benefits and risks of TA for PPH prevention

Benefits	Risks
Less postpartum blood loss	Minor side effects: nausea, vomiting, headache, and skin reactions
Fewer red cell units transfused	Arterial thromboembolism
Less use of additional uterotonics	Venous thromboembolism
Less need for postpartum parenteral iron infusions	Acute kidney injury including renal cortical necrosis and risk of end-stage renal disease
Shorter length of stay	Seizures