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. 2017 Dec 12;18:965. doi: 10.1186/s12864-017-4364-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Sex linked gene expression in the VNO. a and b Principal components analysis (PCA) of all expressed genes in VNO of B6, 129, SWR and SJL strains. c MA plot of gene expression in VNOs from male and female mice. Y-axis indicates the maximal value of fold change (FC) between male and female in log2 scale. Genes that exhibit significant DE are highlighted in color (weighted FC > 2; p < 0.01). d Bar plot of mean normalized expression of Xist in male and female mice. e Stacked bar plot of mean normalized value of Y chromosome linked genes and their X chromosome homologs. Genes expressed from the X and Y chromosomes are labeled red and teal, respectively. Error bars represent standard deviation of expression values