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. Author manuscript; available in PMC: 2017 Dec 13.
Published in final edited form as: J Orthop Res. 2015 Sep 24;34(3):419–426. doi: 10.1002/jor.23036

Figure 4.

Figure 4

F-actin staining on human chondrocytes samples from three patients. After treatment with the 2A3 antibody human chondrocytes show a decrease in the appearance of small cellular protrusions on the cell surface (c) compared to untreated human chondrocytes (a) and human chondrocytes treated with a human immunoglobuline a control (b). Microspikes and the changed cell surface are marked with an arrow (→). The reduction was described semiquantitativly (+, ++, +++) from two blinded investigators.