Table 3.
Predictors of unsuccessful treatment outcome of TB patients from three hospitals, Ethiopian Somali Regional state
| Characteristics | Total n (%) of TB Cases | Unsuccessful outcome n (%) | p-value | COR (95% CI) | P-value | AOR (95% CI) | |
|---|---|---|---|---|---|---|---|
| Sex | Male | 804 (59.0) | 112 (13.9) | 0.35 | 1.16 (0.85, 1.61) | 0.6 | 1.1 (0.8, 1.6) |
| Female | 558 (41.0) | 68 (12.2) | 1 | 1 | |||
| Age group | ≤ 18 | 367 (26.9) | 44 (12.0) | 0.8a | 1 | 1 | |
| 19 to 26 | 326 (23.9) | 43 (13.2) | 1.1 (0.7, 1.7) | ||||
| 27 to 40 | 329 (24.2) | 43 (13.1) | 1.1 (0.7, 1.7) | ||||
| 41+ | 340 (25.0) | 50 (14.7) | 1.3 (0.8, 2.0) | ||||
| HIV Sero-status | Reactive | 63 (4.6) | 10 (15.9) | 0.5 | 1.2 (0.6, 2.5) | 0.4 | 1.4 (0.7, 3.0) |
| Non-reactive (reference) | 1295 (95.4) | 170 (13.1) | 1 | 1 | |||
| Treatment Category | New (reference | 1228 (90.6) | 151 (12.3) | 0.006 | 1 | 0.001 | 1 |
| Re-treatment | 128 (9.4) | 27 (21.1) | 1.9 (1.2, 3.0) | 2.4 (1.4, 3.9) | |||
| TB type | PTB+ | 343 (25.2) | 55 (16.0) | 0.2 | 1.4 (0.9, 2.1) | 0.2 | 1.3 (0.8, 2.0) |
| PTB- | 671 (49.3) | 82 (12.2) | 0.9 (0.7, 1.5) | 0.9 (0.6, 1.3) | |||
| EPTB (reference) | 346 (25.4) | 43 (12.4) | 1 | ||||
| Treatment year | Sept2009 - Aug2010 (refernce) | 94 (6.9) | 8 (8.5) | <0.001 | 1 | < 0.001 | 1 |
| Sept2010 - Aug2011 | 240 (17.6) | 23 (9.6) | 1.1 (0.5, 2.6) | 1.1 (0.5, 2.6) | |||
| Sept2011 - Aug2012 | 299 (22.0) | 18 (6.0) | 0.7 (0.3, 1.6) | 0.7 (0.3, 1.7) | |||
| Sept2012 - Aug2013 | 235 (17.3) | 17 (7.2) | 0.8 (0.3, 2.0) | 0.8 (0.3, 1.9) | |||
| Sept2013 - Aug2014 | 494 (36.3) | 114 (23.1) | 3.2 (1.5, 6.9) | 3.6 (1.7, 7.8) | |||
| Hospital | Kharamara | 522(38.3) | 38(7.3) | <0.001 | 1 | <0.001 | 1 |
| Gode | 227(16.7) | 37(16.3) | 2.5(1.5, 4.0) | 3.1(1.8, 5.1) | |||
| Dege-Habour | 613(45) | 105(17.1) | 2.6(1.8, 3.9) | 3.0(2.0, 4.6) | |||
aIndicates the variable not included in multivariable logistic regression, PTB+ Pulmonary Tuberculosis Smear Positive, PTB Pulmonary Tuberculosis Smear Negative, EPTB Extra-Pulmonary Tuberculosis