Table II.
Anthropometric and metabolic variables at baseline and after 3 months in obese subjects (n = 15; 5 males, 10 females)
| Parameter | Baseline | 3 months | P-value |
|---|---|---|---|
| Body weight [kg] | 109 ±22 | 104 ±23 | < 0.001 |
| BMI [kg/m2] | 38 ±5 | 36 ±5 | < 0.001 |
| Total cholesterol [mg/dl] | 211 ±32 | 204 ±32 | NS |
| Triglycerides [mg/dl] | 126 ±59 | 91 ±33 | < 0.01 |
| HDL cholesterol [mg/dl] | 51 ±12 | 50 ±11 | NS |
| LDL cholesterol [mg/dl] | 135 ±26 | 136 ±26 | NS |
| Apolipoprotein B [mg/dl] | 92 ±17 | 84 ±21 | NS |
| Apolipoprotein A1 [mg/dl] | 139 ±21 | 129 ±20 | NS |
| Apolipoprotein E [mg/l] | 43 ±6 | 38 ±9 | 0.04 |
| Glucose [mg/dl] | 96 ±10 | 93 ±8 | NS |
| Insulin [mU/ml] | 12.9 ±3.6 | 10.0 ±3.2 | NS |
| HOMA index | 3.2 ±0.9 | 2.3 ±0.7 | 0.07 |
| PCSK9 [ng/ml] | 207 ±54 | 218 ±57 | NS |
Values are given as mean ± SD. BMI – body mass index, HDL-C – high-density lipoprotein cholesterol, LDL-C – low-density lipoprotein cholesterol, HOMA – homeostasis model assessment, PCSK9 – proprotein convertase subtilisin/kexin type 9.