Table 3.
Hazard ratio (95% CI) | P | |
---|---|---|
OS | ||
Transplant in 2012-2014 | 0.90 (0.57-1.42) | .65 |
Age, per year | 1.00 (0.99-1.02) | .49 |
RAEB-1 or –2 | 1.54 (0.82-2.89) | .18 |
Transformation to AML | 2.00 (1.07-3.74) | .031 |
Non-CR at transplant | 1.88 (1.24-2.86) | .003 |
Bone marrow vs peripheral blood* | 0.90 (0.56-1.47) | .68 |
Female donor to male recipient | 1.61 (1.06-2.44) | .026 |
CMV-positive recipient | 1.53 (0.95-2.46) | .078 |
≥2 HLA loci mismatch | 1.22 (0.69-2.16) | .49 |
MAC | 1.65 (1.05-2.60) | .032 |
TBI | 1.20 (0.75-1.92) | .44 |
In vivo TCD | 0.96 (0.48-1.92) | .91 |
Ex vivo TCD | 0.74 (0.32-1.71) | .48 |
PT-CY | 0.45 (0.20-1.01) | .054 |
PFS | ||
Transplant in 2012-2014 | 0.92 (0.59-1.42) | .70 |
Age, per year | 1.01 (0.99-1.02) | .40 |
RAEB-1 or −2 | 1.35 (0.76-2.40) | .31 |
Transformation to AML | 1.74 (0.98-3.09) | .060 |
Non-CR at transplant | 1.91 (1.28-2.84) | .001 |
Bone marrow vs peripheral blood* | 1.12 (0.72-1.72) | .62 |
Female donor to male recipient | 1.50 (1.00-2.24) | .049 |
CMV=positive recipient | 1.35 (0.87-2.10) | .18 |
≥2 HLA loci mismatch | 1.13 (0.66-1.92) | .66 |
MAC | 1.55 (1.01-2.39) | .045 |
TBI | 1.12 (0.72-1.75) | .61 |
In vivo TCD | 0.89 (0.47-1.69) | .73 |
Ex vivo TCD | 0.75 (0.34-1.66) | .48 |
PT-CY | 0.50 (0.24-1.02) | .056 |
NRM | ||
Transplant in 2012-2014 | 0.91 (0.53-1.54) | .72 |
Age, per year | 1.01 (0.99-1.03) | .22 |
RAEB-1 or −2 | 1.12 (0.57-2.22) | .74 |
Transformation to AML | 1.62 (0.83-3.17) | .16 |
Non-CR at transplant | 1.88 (1.24-2.86) | .003 |
Bone marrow vs peripheral blood* | 0.90 (0.56-1.47) | .68 |
Female donor to male recipient | 1.61 (1.06-2.44) | .026 |
CMV-positive recipient | 1.53 (0.95-2.46) | .078 |
≥2 HLA loci mismatch | 1.22 (0.69-2.16) | .49 |
MAC | 1.65 (1.05-2.60) | .032 |
TBI | 1.20 (0.75-1.92) | .44 |
In vivo TCD | 0.96 (0.48-1.92) | .91 |
Ex vivo TCD | 0.74 (0.32-1.71) | .48 |
PT-CY | 0.46 (0.21-1.01) | .054 |
Comparison of bone marrow or peripheral blood as the source of stem cells, the reference is peripheral blood.