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. 2017 Sep 27;1(22):1876–1883. doi: 10.1182/bloodadvances.2017007146

Table 3.

Multivariable analysis for the whole group

Hazard ratio (95% CI) P
OS
 Transplant in 2012-2014 0.90 (0.57-1.42) .65
 Age, per year 1.00 (0.99-1.02) .49
 RAEB-1 or –2 1.54 (0.82-2.89) .18
 Transformation to AML 2.00 (1.07-3.74) .031
 Non-CR at transplant 1.88 (1.24-2.86) .003
 Bone marrow vs peripheral blood* 0.90 (0.56-1.47) .68
 Female donor to male recipient 1.61 (1.06-2.44) .026
 CMV-positive recipient 1.53 (0.95-2.46) .078
 ≥2 HLA loci mismatch 1.22 (0.69-2.16) .49
 MAC 1.65 (1.05-2.60) .032
 TBI 1.20 (0.75-1.92) .44
 In vivo TCD 0.96 (0.48-1.92) .91
 Ex vivo TCD 0.74 (0.32-1.71) .48
 PT-CY 0.45 (0.20-1.01) .054
PFS
 Transplant in 2012-2014 0.92 (0.59-1.42) .70
 Age, per year 1.01 (0.99-1.02) .40
 RAEB-1 or −2 1.35 (0.76-2.40) .31
 Transformation to AML 1.74 (0.98-3.09) .060
 Non-CR at transplant 1.91 (1.28-2.84) .001
 Bone marrow vs peripheral blood* 1.12 (0.72-1.72) .62
 Female donor to male recipient 1.50 (1.00-2.24) .049
 CMV=positive recipient 1.35 (0.87-2.10) .18
 ≥2 HLA loci mismatch 1.13 (0.66-1.92) .66
 MAC 1.55 (1.01-2.39) .045
 TBI 1.12 (0.72-1.75) .61
 In vivo TCD 0.89 (0.47-1.69) .73
 Ex vivo TCD 0.75 (0.34-1.66) .48
 PT-CY 0.50 (0.24-1.02) .056
NRM
 Transplant in 2012-2014 0.91 (0.53-1.54) .72
 Age, per year 1.01 (0.99-1.03) .22
 RAEB-1 or −2 1.12 (0.57-2.22) .74
 Transformation to AML 1.62 (0.83-3.17) .16
 Non-CR at transplant 1.88 (1.24-2.86) .003
 Bone marrow vs peripheral blood* 0.90 (0.56-1.47) .68
 Female donor to male recipient 1.61 (1.06-2.44) .026
 CMV-positive recipient 1.53 (0.95-2.46) .078
 ≥2 HLA loci mismatch 1.22 (0.69-2.16) .49
 MAC 1.65 (1.05-2.60) .032
 TBI 1.20 (0.75-1.92) .44
 In vivo TCD 0.96 (0.48-1.92) .91
 Ex vivo TCD 0.74 (0.32-1.71) .48
 PT-CY 0.46 (0.21-1.01) .054
*

Comparison of bone marrow or peripheral blood as the source of stem cells, the reference is peripheral blood.