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. 2017 Sep 8;1(20):1717–1728. doi: 10.1182/bloodadvances.2017006023

Table 2.

Genome-wide significant associations with the C allele in rs11980379 (IKZF1) and B-ALL by sex in EAs

Sex N cases (Cohort 1/Cohort 2) Cohort 1 Cohort 2 ORmeta (95% CI) Pmeta I2 (P)
OR (95% CI) P OR (95% CI) P
Male 219/53 1.9 (1.4, 2.3) 1.5 × 10−7 1.5 (0.9, 2.2) .05 1.8 (1.2, 2.5) 3.8 × 10−8 80.2 (.02)
Female 145/29 1.2 (0.9, 1.6) .13 1.4 (0.6, 2.1) .3 1.3 (0.9, 1.7) .06

I2 and P reflect heterogeneity in the SNP associations with B-ALL between males and females.

OR, odds ratio of logistic additive model risk is presented in terms of the C (minor) allele.