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. 2017 Aug 23;1(20):1628–1631. doi: 10.1182/bloodadvances.2017006767

Figure 1.

Figure 1.

Plasma levels of VWF:Ag and ADAMTS13:AC, the platelet counts during normal pregnancy, and changes of plasma levels of VWF:Ag and ADAMTS13:AC in patients with preeclampsia and patients with HELLP syndrome. (A) Plasma levels of VWF:Ag and ADAMTS13:AC, and platelet counts, in normal pregnant women. Plasma VWF:Ag levels increased during pregnancy and peak levels were found in the third trimester of normal pregnancy, but these decreased rapidly in the postpartum period (top panel). Plasma ADAMTS13:AC levels decreased progressively, even after delivery (middle panel). Platelet counts slightly decreased during pregnancy but were within the normal range (bottom panel). (B) Comparison of plasma VWF:Ag and ADAMTS13:AC between normal pregnant women, pregnant women with preeclampsia, and women with HELLP syndrome in the postpartum period. Plasma levels of VWF:Ag in women with HELLP syndrome were significantly higher than those in normal pregnant women in the postpartum period (top panel, 352.0% vs 179.5%, P < .001). There were no statistical differences in ADAMTS13:AC between the 3 groups (bottom panel: normal pregnancy, 52.1%; preeclampsia, 50.9%; and HELLP syndrome, 50.5%). N.S., not significant.