Table 3. Summary table of melting temperatures as derived from thermal shift assays.

	no RNA	cSLA12	SLA12	Duplex RNA
WT	37.5 ± 0.021	40.5 ± 0.071	42.0 ± 0.16	41.1 ± 0.19
D290A	35.5 ± 0.11	39.2 ± 0.050	41.1 ± 0.49	39.4 ± 0.11
R538A	38.0 ± 0.071	37.7 ± 0.049	38.9 ± 0.15	38.7 ± 0.18
G540P	35.2 ± 0.18	38.4 ± 0.12	39.9 ± 0.071	39.3 ± 0.28