Figure 2.

Variation in Conventional T Cell Phenotypes Across CC-RIX Lines

(A–K) Further analysis of cells subtypes, activation status, and functional profiles across CC-RIX at steady state. Frequencies of CD8+ cells that are Ki67+ (A), CD44+ (B), CD62L− (C) IFNγ+ (D), or IL-17+ (E) are shown at the top; frequencies of CD4+ cells that are Ki67+ (F), Tbet+ (G), IFNγ+ (H), IL-17+ (I), CD44+ (J), and CD62L− (K) are shown at the bottom. The average value for the indicated phenotype of each CC-RIX line (n = 3) is plotted in black in ascending order on the x axis. B6 (red) and BALB/c (blue) baseline values are plotted for comparison. All values represent uninfected controls.

Error bars show ± SEM.