Table 4.

Cox regression of cardiovascular events and cardiovascular event-free survival for ESA-treated vs untreated patients, adjusted for confounders

	HR	95% CI	P
Cardiovascular event
Unadjusted
ESA treatment	1.28	0.68-2.42	.445
Adjusted*
ESA treatment	1.24	0.66-2.34	.507
Presence of another cytopenia	1.92	1.07-3.42	.028
Cardiovascular event or death
Unadjusted
ESA treatment	1.21	0.88-1.66	.234
Adjusted†
ESA treatment	0.94	0.67-1.31	.693
Presence of another cytopenia	2.06	1.54-2.75	< .001
Hemoglobin, g/L	0.98	0.97-0.99	< .001
Age, years	1.03	1.01-1.06	.001
Male sex	1.55	1.15-2.08	.004
Comorbidity index	1.13	1.03-1.23	.006

^*Adjusted for presence of a cytopenia.

^†Adjusted for presence of a cytopenia, hemoglobin, age, sex, and comorbidity index.