Table 1. Sex, age and diabetes-related autoantibodies profile (GAD65, IA2, IAA) in newly diagnosed T1D patients at disease onset used to define percentages of GAD65 pentamer reactive NK cells and their phenotypical characterization.
| Newly diagnosed T1D patient | Sex | Age at onset (years,months) | GAD65 Abs (< 1 U/ml) | IA2 Abs (< 1.1 U/ml) | IAA (< 7%) |
|---|---|---|---|---|---|
| 1* | F | 12.1 | 24 | 1.1 | 2 |
| 2*§ | F | 13.9 | 4.6 | 0.1 | 4.6 |
| 3 | F | 6.9 | 0.3 | 0.1 | 4.0 |
| 4 | M | 10.6 | 22 | 2.1 | 102 |
| 5 | F | 2.6 | 0.6 | 8 | 8 |
| 6 | M | 2.11 | 0.6 | 0.8 | 24 |
| 7 | F | 17.8 | 2 | 7.3 | 5 |
| 8 | M | 17.10 | 5.3 | 13 | 4 |
| 9 | F | 12.3 | 17 | 0.4 | 9 |
| 10 | M | 7.1 | 1.9 | 24 | 5 |
| 11 | F | 4.9 | 3.7 | 7 | 8.2 |
| 12*§§ | F | 13 | 19 | 10 | 1 |
| 13*§§§ | F | 10.2 | 1.5 | 4 | 14.5 |
| 14 | M | 6.6 | 0.2 | NT | 11 |
| 15 | F | 11 | 5 | 5.1 | 5 |
| 16 | M | 5 | 1.4 | 3.2 | 18 |
| 17 | M | 14.11 | 61.4 | 1.7 | 19.7 |
| 18 | M | 13.3 | 0.4 | 0.6 | 7 |
| 19 | M | 13.8 | 1 | 0.6 | 6 |
| 20 | F | 9.3 | 2.7 | 4 | 6.5 |
| 21* | F | 12.7 | 1.6 | 0.4 | 6 |
| 22* | F | 14.2 | 28 | 7.5 | 5 |
| 23* | M | 12.7 | 13 | 10 | 9 |
| 24* | F | 5.8 | 19 | 14 | 9.1 |
| 25* | M | 4.1 | 0.2 | 0.1 | 1 |
| 26* | F | 6.9 | 0.3 | 0.1 | 4 |
| 27* | M | 9.9 | 0.3 | 11 | 6 |
| 28* | F | 10.4 | 5 | 4.6 | 8.2 |
| 29* | M | 10.2 | 0.1 | 4 | 9 |
| 30* | M | 6.4 | 34 | 19 | 13 |
| 31* | F | 15 | 0.4 | 40 | 7 |
*Patients used for CD3-CD8dull GAD65 pentamer reactive cells characterization.
§Associated celiac disease.
§§Associated thyroiditis, anti-gliadin, anti-transglutaminase Abs.
§§§Associated thyroiditis.