Table 2. Summary of results.

Animal #	Treatment	Serology (longitudinal)	Xenodiagnosis			In vivo culture		PCR/RT-PCR
		OspA(A) OspC (C) OppA2 (O) DbpA (D) C6	7 mo.	12 mo.	XT RT-PCR	IFA	Nested RT-PCR	5s_23s PCR	Nested RT-PCR
IK14	Doxycycline 28 days	(-)		(+) P,T	(+) ospC	(-)	(-)	(-)	(-)
IL09	Doxycycline28 days	(+)C,O, D,C6 ↓in C6		(+) T	(-)	(+)	(-)	(+)	(-)
IH11	Doxycycline 28 days	(+)C,O, D,C6 ↓in C6; only D+ at necr.	(+) T		(+) ospC	(+)	$\overline{X}{C}_{\mathrm{q}}$ = 16.50 (ospA)	(+)	(-)
IK66	Doxycycline 28 days	(+)C,O, D,C6 ↓in C6, ↑in C	(+) T		(+) ospA	(+)	$\overline{X}{C}_{\mathrm{q}}$ = 21.0 (ospA)	(-)	(-)
IH22	Doxycycline28 days	(+)C,O, D,C6 ↓in C6		(+) P	(+) ospA	(-)	(-)	(-)	(-)
IL75	No treatment	(+)C,O, D,C6 ↓in C6 and C		(+) T	(+) ospA, (+) ospC	(-)	(-)	(-)	(-)
IP67	No treatment	(+)C, D ↓ all by wk20	(+) T		(+) ospA, (+)ospC	(-)	(-)	(-)	(-)
IN16	No treatment	(+)C,O, D,C6 maintained	(+) T	(+) P	(+) ospA, (e) ospC	Contam.	(-)	(+)	(-)
IN05	No treatment	(+)C,O, D,C6 ↓in C6	(+) T	(+) T	(-)	(+)	$\overline{X}{C}_{\mathrm{q}}$ = 22.88 (oppA-2)	(+)	(-)
IP55	No treatment	(+)C,O, D,C6 maintained	(+) T	(+) P,T	(+) ospA, (+) ospC	Contam.	(-)	(+)	(-)

T = tick contents

P = pellet of tick content culture

$\overline{X}{C}_{\mathrm{q}}$ = mean value for Q-PCR quantification cycle