Table 3.

Cox proportional hazards regression models for association of continuous aortic dilation (per one standard deviation) with incident adverse cardiovascular disease events.

	Unadjusted Model			Model 1*			Model 2†			Model 3‡
	HR (95% CI)	P-value	Interaction by sex P-value	HR (95% CI)	P-value	Interaction by sex P-value	HR (95% CI)	P-value	Interaction by sex P-value	HR (95% CI)	P-value	Interaction by sex P-value
AA, per SD	1.74 (1.53–1.99)	<.001	0.78	1.10 (0.93–1.30)	0.25	0.54	1.08 (0.92–1.27)	0.35	0.93	1.02 (0.87–1.21)	0.77	0.58
DTA, per SD	1.90 (1.74–2.07)	<.001	0.02	1.35 (1.17–1.57)	<0.001	0.26	1.23 (1.06–1.43)	0.006	0.32	1.20 (1.03–1.41)	0.02	0.67
IRA, per SD	1.62 (1.48–1.77)	<.001	0.82	1.17 (1.03–1.33)	0.01	0.32	1.10 (0.98–1.23)	0.11	0.14	1.07 (0.94–1.20)	0.30	0.16
LAA, per SD	1.49 (1.37–1.60)	<.001	0.31	1.18 (1.06–1.32)	0.003	0.09	1.14 (1.03–1.26)	0.01	0.048	1.12 (1.01–1.25)	0.03	0.049

^*Model 1= Adjusted for age and sex

^†Model 2= Adjusted for Model 1 + systolic BP, total cholesterol, HDL cholesterol, hypertension treatment, current smoking, and diabetes

^‡Model 3= Adjusted for Model 2 + Coronary artery calcium

AA=ascending thoracic aorta; DTA=descending thoracic aorta; IRA=infrarenal abdominal aorta; LAA=lower abdominal aorta; SD=standard deviation