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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Exp Eye Res. 2017 Jun 29;163:2–16. doi: 10.1016/j.exer.2017.06.020

Table 1.

Chemical composition of normal human meibum and sebum

Component Human meibum (Butovich et al., 2016) Human sebum (Nakahara et al., 2015;
Picardo et al., 2009; Thiboutot, 2004)
Percentage of total lipids, % (w/w)
(O)-Acylated ω-hydroxy fatty acids (OAHFA) 1–5 none reported
Cholesteryl esters 30–40 3–6
Ceramides traces none reported
Free cholesterol <0.5 1–3
Cholesteryl esters of OAHFA 3 none reported
Diacylated diols Reported, not quantitated none reported
Free fatty acids ~0.1–1 6–40
Phospholipids and sphingomyelins <<0.1 none reported
Squalene traces 10–20
Glycerides 1 (mostly, triolein) 20–80
Wax esters 30–48 20–30
HHS Vulnerability Disclosure