Table 1.
Chemical composition of normal human meibum and sebum
Component | Human meibum (Butovich et al., 2016) | Human sebum (Nakahara et al., 2015; Picardo et al., 2009; Thiboutot, 2004) |
---|---|---|
Percentage of total lipids, % (w/w) | ||
(O)-Acylated ω-hydroxy fatty acids (OAHFA) | 1–5 | none reported |
Cholesteryl esters | 30–40 | 3–6 |
Ceramides | traces | none reported |
Free cholesterol | <0.5 | 1–3 |
Cholesteryl esters of OAHFA | 3 | none reported |
Diacylated diols | Reported, not quantitated | none reported |
Free fatty acids | ~0.1–1 | 6–40 |
Phospholipids and sphingomyelins | <<0.1 | none reported |
Squalene | traces | 10–20 |
Glycerides | 1 (mostly, triolein) | 20–80 |
Wax esters | 30–48 | 20–30 |