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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Nat Chem. 2017 Aug 14;9(12):1213–1221. doi: 10.1038/nchem.2835

Figure 2. Examples of the site-selective oxidation of polyol natural products.

Figure 2

a, The oxidations of this series of natural products shows that the reactions occur at secondary over primary alcohols in complex structures. b, The oxidations of this series of natural products that contain multiple secondary alcohols show that the reactions occur at one secondary alcohol over other secondary alcohols. c, Thermodynamically less-favourable oxidations and selective dehydrogenations with stoichiometric amounts of acceptor occur with trifluoroacetophenone as the acceptor. Allylic isomerization occurs over oxidation in the presence of a ruthenium catalyst that contains the bidentate phosphine.