Table 2.
Mean HI results of serum samples from immunized mice
| Group | HI titers at different days post immunization
|
||
|---|---|---|---|
| Day 14 | Day 28 | Day 35 | |
| pBud-H5-GFP | ND | ND | ND |
| PAMAM/pBud-H5-GFP | ND | 3.3±0.4 | 4±0.9 |
| TAT-PAMAM/pBud-H5-GFP | 2.3±0.4 | 4.6±0.8 | 6.3±0.4 |
| TAT-PAMAM/pBud-H5-GFP-IRF3 | 4.9±0 | 6.64±0.4 | 8.9±0.8 |
| PAMAM/pBud | ND | ND | ND |
| Negative control | ND | ND | ND |
Abbreviations: GFP, green fluorescent protein; HI, hemagglutinin inhibition; IRF, interferon-regulatory factor; PAMAM, polyamidoamine; TAT, transactivator of transcription; ND, not detected.