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. 2017 Nov 30;12:8527–8529. doi: 10.2147/IJN.S136939

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© 2017 Kanavi et al. This work is published and licensed by Dove Medical Press Limited

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Distribution of gold nanoparticles (GNPs) after intratumoral injection in a human eye enucleated for uveal melanoma. Note rather diffuse infiltration of orange-colored GNPs within the sheets of tumor cells ([A and B], hematoxylin and eosin stain, magnifications ×200 and 400, respectively) and the high affinity of the GNPs for intratumoral vascular endothelial lining ([C], hematoxylin and eosin stain, magnification ×200). Image (D) represents lack of presence of GNPs in extratumoral areas such as the cornea, iris, ciliary body, and lens (hematoxylin and eosin stain, magnification ×200).