Table 1.
Genes Enriched in mPFC→NAc and mPFC→VTA Neurons
| Genes enriched in mPFC→NAc | Genes enriched in mPFC→VTA | ||
|---|---|---|---|
| Gene | Gene product | Gene | Gene product |
| NPTX2 | Neuronal pentraxin 2 | TCERG1L | Transcription elongation regulator 1-like |
| F2RL2 | Coagulation factor II (thrombin) receptor-like 2 | POU3F1 | POU domain, class 3, transcription factor 1 |
| FOS | FBJ osteosarcoma oncogene | PTCD3 | Pentatricopeptide repeat domain 3 |
| LCN2 | Lipocalin 2 | CHST8 | Carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| PTGFRN | Prostaglandin F2 receptor negative regulator | IGFBP4 | Insulin-like growth factor binding protein 4 |
| SCCPDH | Saccharopine dehydrogenase | BCL11B (CTIP2) | B cell leukemia/lymphoma 11B |
| TMEM254B | Transmembrane protein 254b | PARM1 | Prostate androgen-regulated mucin-like protein 1 |
| BIN2 | Bridging integrator 2 | NRIP3 | Nuclear receptor interacting protein 3 |
| NRN1 | Neuritin 1 | BCL6 | B cell leukemia/lymphoma 6 |
| LY6A | Lymphocyte antigen 6 complex, locus A | DSCAML1 | Down syndrome cell adhesion molecule like 1 |
| CD7 | CD7 antigen | RHBDL3 | Rhomboid, veinlet-like 3 (Drosophila) |
| LY96 | Lymphocyte antigen 96 | GLRA3 | Glycine receptor, alpha 3 subunit |
| IGLC3 | Immunoglobulin lambda constant 3 | NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| TOMM5 | Translocase of outer mitochondrial membrane 5 homolog (yeast) | LOR | Loricrin |
| LRRC3B | Leucine rich repeat containing 3B | VMN1R127 | Vomeronasal 1 receptor 127 |
| KRTAP5-1 | Keratin associated protein 5-1 | SYCP3 | Synaptonemal complex protein 3 |
| ZNRD1 | Zinc ribbon domain containing, 1 | ||
| KLF10 | Kruppel-like factor 10 | ||
| MAP3K8 | Mitogen-activated protein kinase kinase kinase 8 | ||
| CYP11A1 | Cytochrome P450, family 11, subfamily a, polypeptide 1 | ||
| TMEM126A | Transmembrane protein 126A | ||
| CTSH | Cathepsin H | ||
| CNIH3 | Cornichon homolog 3 (Drosophila) | ||
| ANKRD33B | Ankyrin repeat domain 33B | ||
| MPV17 | MpV17 mitochondrial inner membrane protein | ||
| KRT12 | Keratin 12 | ||
| RIMS3 | Regulating synaptic membrane exocytosis 3 | ||
| COX20 | COX20 Cox2 chaperone | ||
| LBP | Lipopolysaccharide binding protein | ||
| HMGN2 | High mobility group nucleosomal binding domain 2 | ||
| SRGN | Serglycin | ||
| FAP | Fibroblast activation protein | ||
| CD33 | CD33 antigen | ||
| SPG21 | Spastic paraplegia 21 homolog (human) | ||
| LOC102641848 | 60S ribosomal protein L15-like | ||
List of candidate genes enriched in mPFC→NAc neurons or enriched in mPFC→VTA neurons. See also Method Details: Molecular profiling experiment, Table S1, and Figure S1.