Table 3.

Univariate predictors of cardiac death and composite outcome in patients with IMR

	Cardiac death		Cardiac death and heart failure
	HR (95% CI)	P value	HR (95% CI)	P value
Age	1.04 (1.01 to 1.07)	0.02	1.06 (1.04 to 1.09)	<0.001
Male	1.00 (0.44 to 2.29)	0.99	1.47 (0.88 to 2.44)	0.14
Hypertension	1.06 (0.55 to 2.02)	0.87	1.62 (1.02 to 2.57)	0.04
Dyslipidaemia	0.97 (0.50 to 1.86)	0.92	1.01 (0.64 to 1.57)	0.98
Diabetes mellitus	1.52 (0.79 to 2.94)	0.21	1.69 (1.09 to 2.65)	0.02
Smoking	1.22 (0.63 to 2.35)	0.56	0.96 (0.61 to 1.53)	0.87
Killip classification	2.54 (1.95 to 3.30)	<0.001	2.16 (1.77 to 2.64)	<0.001
Peak CK	1.15 (1.08 to 1.23)	<0.001	1.11 (1.05 to 1.17)	<0.001
Creatinine	1.30 (1.19 to 1.42)	<0.001	1.23 (1.14 to 1.34)	<0.001
Prior MI	2.37 (1.04 to 5.42)	0.04	1.92 (1.04 to 3.54)	0.04
Anterior MI	0.80 (0.42 to 1.54)	0.51	1.23 (0.79 to 1.91)	0.36
PCI	1.05 (0.37 to 2.96)	0.93	0.70 (0.38 to 1.29)	0.25
Moderate or severe MR	14.90 (7.74 to 28.68)	<0.001	5.13 (3.19 to 8.25)	<0.001
β-blocker	0.38 (0.20 to 0.73)	0.004	0.41 (0.26 to 0.64)	<0.001
Statins	0.74 (0.39 to 1.43)	0.37	0.62 (0.39 to 0.96)	0.03

Per 1000 IU/L increments.

CK, creatine kinase; IMR, ischaemic mitral regurgitation; MI, myocardial infarction; PCI, percutaneous coronary intervention.