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. 2017 Oct 24;117(11):1723–1731. doi: 10.1038/bjc.2017.347

Table 3. Cumulative risk (excess risk) of specified adverse health outcomes by 45 years from diagnosis of all childhood cancers combined except leukaemia for specific NCSI Levels.

  NCSI Level of Clinical Care
Adverse health outcome 1 2 3
Any subsequent primary neoplasm 5% (2-fold) 14% (4-fold) 21% (8-fold)
Any potentially treatment related non-neoplastic death 2% (2-fold) 4% (3-fold) 8% (7-fold)
Any potentially treatment related non-fatal non-neoplastic condition 14% 27% 40%
Overall cumulative risk 21% 45% 69%