Fig. 2.

Vertical read blocks and variant calling bias visualization. Typical vertically enriched read blocks are illustrated in (2a and 2b). Aspecific fragments, not corresponding to predicted amplicons are shown in (2a) and variants restricted to read ends are shown in (2b). Called variants are indicated by a red dashed rectangular. Reads are given in blue and pink colored horizontal bars, indicating read orientation. Theoretical manufacturer designed Haloplex probes are presented in green colored horizontal bars below their corresponding enriched reads