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. 2017 Oct 3;117(12):1883–1887. doi: 10.1038/bjc.2017.350

Table 2. Adjusted hazard ratio associated with a 100-mSv increase in cumulative exposure.

  Minimum latent period 10 years assumed for solid cancer and 2 years for leukaemia
Minimum latent period 5 years assumed for solid cancer and 2 years for leukaemia
Cancer site Casea HR100mSvb 90% CIb P-valueb Casea HR100mSvb 90% CIb P-valueb
All cancers 249 1.05 (1.00, 1.08) 0.04 282 1.05 (1.00, 1.08) 0.03
All cancers excluding leukaemia 241 1.04 (1.00, 1.08) 0.08 274 1.04 (1.00, 1.08) 0.05
All solid cancers 236 1.04 (1.00, 1.08) 0.07 269 1.04 (1.01, 1.08) 0.04
 Female breast 35 1.11 (1.05, 1.20) 0.008 40 1.12 (1.04, 1.17) 0.002
 Cervix uteri 24 1.10 (0.96, 1.20) 0.10 28 1.09 (0.97, 1.17) 0.13
 Lung 24 1.10 (1.00, 1.17) 0.05 27 1.12 (1.04, 1.18) 0.004
 Thyroid gland 20 1.06 (0.83, 1.17) 0.52 25 1.03 (0.80, 1.15) 0.75
 Liver 18 1.05 (0.88, 1.15) 0.52 19 1.04 (0.88, 1.14) 0.57
 Stomach 13 1.08 (0.92, 1.19) 0.27 15 1.10 (0.97, 1.19) 0.10
 Rectum 16 1.03 (0.73, 1.17) 0.78 17 1.02 (0.71, 1.16) 0.87
Leukaemia excluding MM&CLLc 8 1.18 (1.04, 1.28) 0.006 8 1.18 (1.04, 1.28) 0.006
Leukaemia excluding CLL 11 1.15 (1.03, 0.24) 0.012 11 1.15 (1.03, 1.24) 0.012
a

Cancers with minimum latent periods (leukaemia:2 years; solid cancers:10 years or 5 years).

b

HR were adjusted for initial exposure age, 90% CI were partial likelihood-based, and P-values were two-sided.

c

CLL=chronic lymphocitic leukaemia; MM=multiple myeloma.