Table 2. Adjusted hazard ratio associated with a 100-mSv increase in cumulative exposure.
Minimum latent period 10 years assumed for solid cancer and 2 years for leukaemia |
Minimum latent period 5 years assumed for solid cancer and 2 years for leukaemia |
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---|---|---|---|---|---|---|---|---|
Cancer site | Casea | HR100mSvb | 90% CIb | P-valueb | Casea | HR100mSvb | 90% CIb | P-valueb |
All cancers | 249 | 1.05 | (1.00, 1.08) | 0.04 | 282 | 1.05 | (1.00, 1.08) | 0.03 |
All cancers excluding leukaemia | 241 | 1.04 | (1.00, 1.08) | 0.08 | 274 | 1.04 | (1.00, 1.08) | 0.05 |
All solid cancers | 236 | 1.04 | (1.00, 1.08) | 0.07 | 269 | 1.04 | (1.01, 1.08) | 0.04 |
Female breast | 35 | 1.11 | (1.05, 1.20) | 0.008 | 40 | 1.12 | (1.04, 1.17) | 0.002 |
Cervix uteri | 24 | 1.10 | (0.96, 1.20) | 0.10 | 28 | 1.09 | (0.97, 1.17) | 0.13 |
Lung | 24 | 1.10 | (1.00, 1.17) | 0.05 | 27 | 1.12 | (1.04, 1.18) | 0.004 |
Thyroid gland | 20 | 1.06 | (0.83, 1.17) | 0.52 | 25 | 1.03 | (0.80, 1.15) | 0.75 |
Liver | 18 | 1.05 | (0.88, 1.15) | 0.52 | 19 | 1.04 | (0.88, 1.14) | 0.57 |
Stomach | 13 | 1.08 | (0.92, 1.19) | 0.27 | 15 | 1.10 | (0.97, 1.19) | 0.10 |
Rectum | 16 | 1.03 | (0.73, 1.17) | 0.78 | 17 | 1.02 | (0.71, 1.16) | 0.87 |
Leukaemia excluding MM&CLLc | 8 | 1.18 | (1.04, 1.28) | 0.006 | 8 | 1.18 | (1.04, 1.28) | 0.006 |
Leukaemia excluding CLL | 11 | 1.15 | (1.03, 0.24) | 0.012 | 11 | 1.15 | (1.03, 1.24) | 0.012 |
Cancers with minimum latent periods (leukaemia:2 years; solid cancers:10 years or 5 years).
HR were adjusted for initial exposure age, 90% CI were partial likelihood-based, and P-values were two-sided.
CLL=chronic lymphocitic leukaemia; MM=multiple myeloma.