Table 1. Description of clinical variables of mCRC samples.
N | % | |
---|---|---|
Sex | ||
Male | 20 | 58.8 |
Female | 14 | 41.4 |
Age at diagnosis | ||
<50 | 11 | 32.4 |
⩾50 | 23 | 67.6 |
Localisation | ||
Colon right-sided | 10 | 29.4 |
Colon left-sided | 15 | 44.1 |
Rectum | 9 | 26.5 |
Treatment | ||
Cetuximab | 20 | 58.8 |
Panitumumab | 14 | 41.2 |
Associated chemotherapy | ||
Monotherapy | 4 | 11.8 |
Irinotecan | 5 | 14.8 |
FOLFIRI | 21 | 61.8 |
FOLFOX | 4 | 11.8 |
RECIST score | ||
Complete response | 0 | 0.00 |
Partial response | 11 | 32.4 |
Stabilisation | 11 | 32.4 |
Progression | 12 | 35.3 |
Line of treatment | ||
First line | 4 | 11.8 |
Second line | 13 | 38.2 |
Third line | 17 | 50.0 |
Number of metastatic sites | ||
1 | 12 | 35.3 |
2 | 13 | 38.2 |
3 | 9 | 26.5 |
Mutations in
PIK3CA | ||
WT | 29 | 85.3 |
Mutant | 5 | 14.7 |
Mutations in
BRAF | ||
WT | 33 | 97.1 |
Mutated | 1 | 2.9 |
Abbreviations: mCRC=metastatic colorectal cancer; WT=wild type.