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Atorvastatin (10–200 µM) induces morphological changes in TM cells. Treatment with 10–200 µM atorvastatin for 24 h caused dose-dependent changes in the shape of TM cells in confluent culture, including cell rounding and cell-cell separation, compared with control cells. Similar results were observed in three independent experiments (scale bar, 100 µm). TM, trabecular meshwork.
