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Atorvastatin-induced changes in cell shape, F-actin, focal adhesions and adherens junctions in TM cells. After treatment with atorvastatin (10–200 µM) for 24 h, TM cells were fixed and stained for nuclei (blue), F-actin (green) and vinculin (red) or β-catenin (red). In TM cells, the change of actin cytoskeletal organization and distribution of focal adhesions induced by atorvastatin was in accordance with cell shape changes (scale bar, 100 µm). TM, trabecular meshwork.
