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. Author manuscript; available in PMC: 2017 Dec 14.
Published in final edited form as: J Med Chem. 2017 Sep 13;60(18):7935–7940. doi: 10.1021/acs.jmedchem.7b00921

Figure 3.

Figure 3

Preliminary safety data of 11 – 14 (A – C) and their impact on tumor multiplicity (D) (n=5 for 11 – 14 and n=10 for NNK group). Statistical analysis was performed with ONE-WAY ANOVA, followed by Dunnett’s test of each treatment group relative to the NNK control group; **** p<0.0001.