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. 2017 Dec 11;10:5863–5872. doi: 10.2147/OTT.S149361

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© 2017 Peng et al. This work is published and licensed by Dove Medical Press Limited

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UHRF2 was negatively associated with E-cadherin expression in ICC.

Notes: (A) High expression of UHRF2 and low expression of E-cadherin, and low expression of UHRF2 and high expression of E-cadherin are shown. Scale bar: 100, 200 μm. (B) The relationship between UHRF2 and E-cadherin in ICC patients; the protein expression of UHRF2 was significantly negatively correlated with E-cadherin expression. (C) UHRF2 and E-cadherin protein were detected by Western blot analysis. (D) Representative immunofluorescent images of UHRF2 and E-cadherin in ICC cell lines are shown. Scale bars =100 μm. *P<;0.05, **P<;0.01, ***P<;0.001.

Abbreviations: H<E, hematoxylin and eosin; ICC, intrahepatic cholangiocarcinoma; UHRF2, ubiquitin-like with PHD and ring finger domains 2.