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. 2017 Dec 1;23(23-24):1490–1501. doi: 10.1089/ten.tea.2017.0111

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Copyright 2017, Mary Ann Liebert, Inc.

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FIG. 1. — Addition of FGF-2 to cultures of MDPCs from mouse bone fragments and NIH3T3 mouse fibroblasts (3T3) had different effects on Sca-1 and CD166 markers, as measured by flow cytometry analysis. (A) MDPC cultures had an FGF-2 dose-dependent increase in the expression of Sca-1 on D7, compared to D0 baseline and vehicle-treated D7 cultures. 3T3 cells did not respond to FGF-2 in a significant manner. FGF-2 doses shown on graph legend are expressed in ng/mL. **p ≤ 0.01. (B) MDPC exhibited an FGF-2 dose-dependent increase in the expression of CD166 on D7, compared to D0 and vehicle-treated D7 cultures. 3T3 cells did not respond to FGF-2 in a significant manner. FGF-2 doses expressed in ng/mL. **p ≤ 0.01. FGF-2, fibroblast growth factor-2; MDPC, mesenchyme-derived progenitor cell.