Table 1.
Representative lncRNAs associated with poor prognosis among 55 lncRNAs.
| ENSEMBL ID | Gene name | Fold change (Tumor/Normal) | Survival outcome | Log-rank p-value | Cox p-value | HR (95% CI) |
|---|---|---|---|---|---|---|
| LncRNAs up-modulated in tumors | ||||||
| ENSG00000250874 | CTC-480C2.1 | 148.6 | Reduced OS | 0.0006 | 0.1447 | --- |
| ENSG00000271127 | LL22NC03-N64E9.1 | 24.4 | Reduced OS | 0.0247 | 0.0351 | 1.5 (1.03 – 2.27) |
| ENSG00000261327 | RP11-863P13.3 | 18.5 | Reduced DFS | 0.0423 | 0.133 | --- |
| ENSG00000260162 | RP11-863P13.1 | 17.1 | Reduced DFS | 0.015 | 0.0576 | --- |
| ENSG00000249395 | CASC9 | 14.5 | Reduced OS | 0.0047 | 0.0498 | 1.5 (1 – 2.18) |
| ENSG00000256268 | RP11-221N13.3 | 14.1 | Reduced OS | 0.0462 | 0.686 | --- |
| ENSG00000267284 | RP11-397A16.1 | 12.4 | Reduced OS | 0.0109 | 0.0457 | 1.5 (1 – 2.23) |
| ENSG00000250546 | RP11-8L2.1 | 11.2 | Reduced OS | 0.0213 | 0.1138 | --- |
| ENSG00000234695 | AC002076.10 | 9.2 | Reduced OS | 0.0204 | 0.0285 | 1.5 (1.05 – 2.30) |
| ENSG00000225548 | AC098973.2 | 8.8 | Reduced OS | 0.016 | 0.2062 | --- |
| ENSG00000234902 | AC007879.2 | 5.7 | Reduced OS | 0.0009 | 0.112 | --- |
| ENSG00000271826 | PLS3-AS1 | 4.2 | Reduced OS | 0.019 | 0.5359 | --- |
| ENSG00000251381 | LINC00958 | 3.5 | Reduced OS | 0.0139 | 0.3 | --- |
| ENSG00000237152 | DLEU7-AS1 | 3 | Reduced OS | 0.0018 | 0.00348 | 1.8 (1.2 – 2.6) |
| ENSG00000230002 | ALMS1-IT1 | 2.9 | Reduced OS | 0.0107 | 0.0102 | 1.7 (1.13 – 2.51) |
| ENSG00000245522 | RP11-540A21.2 | 2.9 | Reduced OS | 0.0408 | 0.4654 | --- |
| ENSG00000232725 | U52111.14 | 2.8 | Reduced DFS | 0.0432 | 0.21 | --- |
| ENSG00000254551 | RP11-727A23.7 | 2.7 | Reduced DFS | 0.0203 | 0.306 | --- |
| ENSG00000259901 | --- | 2.6 | Reduced OS & DFS | <0.05 | 0.089 (OS) 0.542 (DFS) | --- |
| ENSG00000172965 | MIR4435-1HG | 2.2 | Reduced OS & DFS | <0.003 | 0.0955 | --- |
|
| ||||||
| LncRNAs down-modulated in tumors | ||||||
| ENSG00000258616 | RP11-369C8.1 | -76.1 | Increased DFS | 0.0371 | 0.297 | --- |
| ENSG00000228789 | HCG22 | -21.9 | Increased OS | 0.002 | 0.2799 | --- |
| ENSG00000233987 | AC106706.1 | -21.1 | Increased OS | 0.0237 | 0.01534 | 0.41 (0.19 – 0.84) |
| ENSG00000231062 | AC103563.9 | -15.5 | Increased OS | 0.0127 | 0.0905 | --- |
| ENSG00000253389 | RP11-930P14.1 | -12.7 | Increased OS | 0.0388 | 0.09896 | --- |
| ENSG00000225129 | RP4-614C15.2 | -9.1 | Increased OS | 0.0101 | 0.0122 | 0.31 (0.12 – 0.77) |
| ENSG00000237530 | RP3-449H6.1 | -8.7 | Increased OS | 0.0093 | 0.05069 | --- |
| ENSG00000197585 | AC107218.3 | -8.1 | Increased OS | 0.0234 | 0.0238 | 0.62 (0.41 – 0.94) |
| ENSG00000259459 | RP11-321G12.1 | -8 | Increased OS | 0.0347 | 0.15003 | --- |
| ENSG00000260402 | RP11-56L13.1 | -7.4 | Increased OS | 0.0117 | 0.00206 | 0.54 (0.37 – 0.80) |
| ENSG00000223678 | RP11-311H10.4 | -6.8 | Increased OS | 0.0382 | 0.00528 | 0.45 (0.26 – 0.79) |
| ENSG00000266114 | RP11-963H4.5 | -6.5 | Increased OS | 0.0466 | 0.042 | 0.66 (0.45 – 0.98) |
| ENSG00000248799 | CTC-548H10.2 | -5.7 | Increased OS & DFS | <0.05 | 0.8832 (OS) 0.182 (DFS) | --- |
| ENSG00000249797 | CTD-3179P9.1 | -5.5 | Increased OS | 0.0059 | 0.00816 | 0.59 (0.39 – 0.87) |
| ENSG00000262133 | RP11-676J12.6 | -5 | Increased OS | 0.0343 | 0.916 | --- |
| ENSG00000232803 | SLCO4A1-AS1 | -4.4 | Increased DFS | 0.0019 | 0.145 | --- |
| ENSG00000233070 | ZFY-AS1 | -4.3 | Increased OS | 0.0004 | 0.00389 | 0.50 (0.32 – 0.80) |
| ENSG00000233529 | HCG21 | -3.4 | Increased OS | 0.0108 | 0.1142 | --- |
| ENSG00000260931 | --- | -3.4 | Increased OS | 0.0035 | 0.01234 | 0.61 (0.41 – 0.90) |
| ENSG00000230790 | AC012456.4 | -3.3 | Increased OS & DFS | <0.02 | 0.10733 (OS) 0.796 (DFS) | --- |
CI: Confidence interval
DFS: Disease-free survival
HR: Hazard ratio
OS: Overall survival