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. Author manuscript; available in PMC: 2018 Feb 9.
Published in final edited form as: Nature. 2017 Aug 9;548(7667):338–342. doi: 10.1038/nature23450

Figure 1. Mettl3 KO naïve T cells do not promote disease in CD45RB-High adoptive transfer colitis mouse model.

Figure 1

a, Body weight changes after naïve T cell adoptive transfer into Rag2−/− host mice (n=10), 2-way ANOVA. b, c, Endoscopic colitis scores and representative pictures of H&E staining of the colon from Rag2−/− receiving WT and KO naive T cells 8 weeks after transfer (n=10), unpaired t test. d, FACS analysis of transferred T cells in colon tissues (n=3), unpaired t test. n=number of biological replicates. p***<0.001, p****<0.0001.