Table 1.

Summary of the studies that were used for CYP2A6 sequencing and CYP2A6 genotype-phenotype analyses.

Study Title	Number of subjects analyzed	Sequencing or Genotyping Approach	Purpose of sequencing or genotyping	Reference for original study
Liver Bank	43	CYP2A6-Specific sequencing	Exploratory sequencing	Tanner, Prasad [17]
Pharmacokinetic Study	57	CYP2A6-Specific sequencing	Exploratory sequencing	Mwenifumbo, Sellers [24]
KIS2	26	CYP2A6-Specific sequencing	Exploratory sequencing	Ho, Mwenifumbo [25]
KIS3	86	CYP2A6-Specific sequencing	Exploratory sequencing	Cox, Nollen [26]
Liver Bank	327	PGRN-Sequencing, and TaqMan SNP genotyping	Identify SNPs for genotype-phenotype analyses	Tanner, Prasad [17]
PNAT	641	Genotyped via GWAS SNP calls	Identify SNPs for genotype-phenotype analyses	Lerman, Schnoll [7]