Table 4.
Diplotype Group # |
Full Diplotype | N in liver bank | CYP2A6 activity (nicotine metabolism, nmol/min/mg), mean of diplotype group |
---|---|---|---|
Reference | G T T T A / G T T T A | 17 | 0.07 |
| |||
1 | G C C G G / G C C G G | 64 | 0.13 |
2 | G T T T A / G C C G G | 60 | 0.09 |
3 | G T T G A / G C C G G | 22 | 0.12 |
4 | G C C G A / G C C G G | 17 | 0.10 |
5 | G T T T A / G T T G A | 15 | 0.08 |
| |||
6 | G C C G G / A C C G G | 14 | 0.11 |
7 | G T T T A / A C C G G | 12 | 0.14 |
8 | G T T T A / G C C G A | 8 | 0.08 |
9 | G T T G A / G C C G A | 5 | 0.06 |
10 | G T T G A / A C C G G | 4 | 0.03 |
11 | G C C G A / A C C G G | 3 | 0.31 |
12 | G T T G A / G T T G A | 2 | 0.04 |
13 | G T T T A / G C C T G | 2 | 0.08 |
14 | A C C G G / A C C G G | 1 | 0.03 |
15 | G C C G A / G C C G A | 1 | 0.01 |
16 | G C T G A / A C C G G | 1 | 0.08 |
17 | G C T G A / G C C G G | 1 | 0.01 |
18 | G C T T A / G C C G G | 1 | 0.04 |
19 | G T C G A / G C C G A | 1 | 0.23 |
20 | G T C G A / G C C G G | 1 | 0.03 |
21 | G T C G G / A C C G G | 1 | 0.12 |
22 | G T C G G / G C C G G | 1 | 0.08 |
23 | G T T G A / G T C G G | 1 | 0.19 |
24 | G T T T G / G T C G G | 1 | 0.30 |
. Full reference diplotype is bolded