Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Pharmacogenet Genomics. 2018 Jan;28(1):7–16. doi: 10.1097/FPC.0000000000000317

Table 4.

Five-SNP phased diplotypes predicted in donors in the liver bank

Diplotype Group
#
Full Diplotype N in liver bank CYP2A6 activity
(nicotine metabolism, nmol/min/mg),
mean of diplotype group
Reference G T T T A / G T T T A 17 0.07

1 G C C G G / G C C G G 64 0.13
2 G T T T A / G C C G G 60 0.09
3 G T T G A / G C C G G 22 0.12
4 G C C G A / G C C G G 17 0.10
5 G T T T A / G T T G A 15 0.08

6 G C C G G / A C C G G 14 0.11
7 G T T T A / A C C G G 12 0.14
8 G T T T A / G C C G A 8 0.08
9 G T T G A / G C C G A 5 0.06
10 G T T G A / A C C G G 4 0.03
11 G C C G A / A C C G G 3 0.31
12 G T T G A / G T T G A 2 0.04
13 G T T T A / G C C T G 2 0.08
14 A C C G G / A C C G G 1 0.03
15 G C C G A / G C C G A 1 0.01
16 G C T G A / A C C G G 1 0.08
17 G C T G A / G C C G G 1 0.01
18 G C T T A / G C C G G 1 0.04
19 G T C G A / G C C G A 1 0.23
20 G T C G A / G C C G G 1 0.03
21 G T C G G / A C C G G 1 0.12
22 G T C G G / G C C G G 1 0.08
23 G T T G A / G T C G G 1 0.19
24 G T T T G / G T C G G 1 0.30
a

. Full reference diplotype is bolded