DCS and DRS skin results—occlusion studies were performed on all pigs using a Hoffman clamp placed over the artery. A skin patch was secured to the artery downstream from the Hoffman clamp via sutures [see Fig. 2(c)]. For pigs 3 and 4, the study began with the Hoffman clamp fully opened (3.2 mm). Incremental clamp tightening () occurred every minute after the first 2 min, with full occlusion reached at 8 min. After 10 min, incremental clamp untightening () occurred every minute until the clamp reached its original position (3.2 mm). (a) and (b) display DCS values calculated from autocorrelation curves measured at skin sites on pigs 1 to 4 using 2- and 5-mm source–detector separations, respectively. (c) and (d) display hemodynamic variables, total [HbT], and extracted from DRS spectra measured at skin sites on pigs 1 to 4. After DRS data acquisition on pig 2, the surgeon reported spontaneous venous congestion in the flap.