Table 1.

Data table of principle of paired design for the faecal markers calprotectin and calgranulin C

		Faecal calgranulin C
		Positive	Negative	Total
Diagnosis: no IBD
Faecal calprotectin	Positive	Concordant (v)	Discordant (w)	v+w
	Negative	Discordant (x)	Concordant (y)	x+y
	Total	v+x	w+y	N−
Diagnosis: IBD
Faecal calprotectin	Positive	Concordant (r)	Discordant (s)	r+s
	Negative	Discordant (t)	Concordant (u)	t+u
	Total	r+t	s+u	N+

Null hypothesis H₀ (specificity): w=x; alternative hypothesis H₁: w≠x.

Null hypothesis H₀ (sensitivity): s=t; alternative hypothesis H₁: s≠t.

IBD, inflammatory bowel disease.